Refactor Capital

Astranis builds the world's most advanced satellites for high orbits, focusing on dedicated satellite broadband and supporting government science, PNT, and communications missions.

64x.com offers digital imaging, web hosting, and design services, including posters, banners, and promotional product imprinting.

Gencove is unlocking the value of genetic data, enabling the most ambitious applications of genomics across industries, including human and agricultural genomics.

Loyalfordogs is a veterinary medicine company focused on extending dogs' lifespans and healthspans through clinical-stage drug development.

Octant is a therapeutics company building small molecule drugs that modulate cellular mechanisms. They focus on next-generation drug discovery using synthetic biology, high throughput chemistry, and AI/ML to target complex diseases, particularly those caused by protein misfolding.

Mythic is a pioneering AI processor company specializing in analog compute-in-memory technology, which delivers significant improvements in energy efficiency and performance for edge AI applications. Their Analog Matrix Processors enable high-performance computing for various sectors, including automotive, robotics, and defense, while drastically reducing power consumption and costs.

YourChoice Therapeutics is a company focused on developing innovative therapeutic solutions.

Miist Therapeutics is setting a new standard in acute care with inhaled therapies that work in seconds, providing instant relief through the peripheral lung.

Using immune organoids and AI to design drugs that work in people from the start, delivering safe and effective therapies without the need for traditional clinical trials.

Adventris is a biotechnology company focusing on cancer immunotherapy.

Granza Bio utilizes the discovery of 'attack particles,' a powerful suite of weapons in the immune system’s arsenal, to transform the fight against diseases such as cancers, autoimmunity, and infections.

Early-stage, first-money-in partner for technically ambitious founders transforming the physical world (energy, defense, infrastructure, space, advanced manufacturing), underwriting high technical and regulatory risk.

Invests in disruptive, technology-focused startups; established in 1999.

Stealthy investor across frontier sectors (space, biotech, AI) making sub-$500K average checks into technically complex startups with exceptional defensibility and operational guidance from GP Rob Ness's 2% Rule.

Seed-stage investor focused on climate and human health that backs founders whose mission is core to product. Wireframe Ventures is built around a people-product-purpose thesis that only backs founders whose mission to improve the health of people and planet is inseparable from their commercial product. The fund has demonstrated strong performance by taking early technical risk in deeptech, biotech, and energy companies, with Fund I yielding two unicorns, two exits, and approximately 70% of portfolio companies raising institutional Series A rounds within 15 months.