Asymmetry Ventures
San Francisco, CA · Invests in US · Website
Check size
🔒 $•• – $••Thesis
Backing transformative startups with exceptional defensibility and civilization-level impact potential. Focus on technical complexity, defensible innovation, and companies solving large-scale problems. Quality over volume approach with selective, thesis-driven investing.
Likely not a fit for
Pure consumer social apps. Traditional enterprise SaaS without defensible innovation. Service-based or labor-intensive models. Low-tech or commodity businesses. Companies without clear technical defensibility.
How they invest
- Lead or follow
- Usually follows
- Typical decision
- ~2 months
- Warm intro
- Preferred
- Involvement
- Takes a board seat
- Fund status
- Actively deploying
- Decision process
- Partnership vote
Partners & team
5 contacts on file
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Atomic Alchemy is building scalable U.S. radioisotope production capabilities in U.S.-based facilities dedicated to producing essential isotopes for healthcare, industry, research, and defense.
BTQ delivers quantum advantage through cost-efficient solutions that create new markets and disrupt existing industries, focusing on post-quantum cryptography and quantum solutions.
Cyberdontics is revolutionizing modern dentistry through advanced imaging, AI, and robotics, helping dentists diagnose and treat patients more effectively.
CytoReason is a biotechnology company that develops AI-powered disease models to improve drug discovery and development processes.
Foresight Mental Health provides therapy and psychiatry services both online and in-person, focusing on immediate availability and a range of mental health services including child and adolescent therapy, maternal mental health, and intensive treatment services.
Frontier Bio develops advanced vascular grafts and tissue platforms for creating engineered tissues. The company focuses on building the foundation for organ-scale tissue engineering.
Genecis Bioindustries is a climate biotech company turning organic waste into sustainable, biodegradable materials, offering a circular economy solution for products’ beginning and end of life.
InpharmD™ is a digital service that provides on-demand drug information to clinical pharmacists, enabling evidence-based care through AI-powered literature searches.
Kernal Bio is a biotech company developing onco-selective mRNA therapeutics aimed at improving cancer patients' survival and quality of life. The company is engineering cells inside the body using AI-designed, selective mRNA and targeted LNP.
New Culture is revolutionizing how cheese is made with animal-free dairy products that stretch, melt, and taste like the real deal. They combine traditional cheese-making and innovative food science to create cheese that is kinder on animals, the planet, and human health.
Orbit Fab is building the in-space propellant supply chain, providing spacecraft refueling services to enable a sustainable and thriving in-space economy.
Recent activity
- Dec 2025
Enlightra
Series A · Participant
- May 2025
PERSIST.AI
Series A · Investor
- Mar 2025
Coreshell
Series A2 · Investor
Asymmetry Ventures in the news
GameDev.net
AI startup Reforged Labs shuts down as the "gap we were selling into is closing"
1 month ago
GameDev.net
AI startup Reforged Labs shuts down as the "gap we were selling into is closing"
1 month ago
Tech.eu
Enlightra exits stealth with $15M to power energy-efficient AI data centre lasers
8 months ago
BetaKit
Mark Cuban-backed TransCrypts closes $20-million CAD seed round
11 months ago
PR Newswire
Coreshell Raises $24M To Commercialize the Lowest-Cost and Domestically-Sourced Lithium-Ion Battery Anode
Mar 2025
Techeconomy
As Seasoned Doctors Exit The Field, SimCare AI Raises $2M to Scale Clinical Training with AI Patients
Mar 2025
The Business Journals
SimCare AI secures seed funding to expand health-care simulation platform
Feb 2025
AlleyWatch
The Weekly Notable Startup Funding Report: 2/17/25
Feb 2025
GeekWire
Wildfire recovery and carbon capture company Mast Reforestation lands $25M
Feb 2025
BioSpace
Rejuvenation Technologies Raises $10.6M Seed Financing Led by Khosla Ventures to Develop mRNA Therapeutics to Reverse Aging
Sep 2023
FinSMEs
NewHomesMate Raises $5.5M in Seed Funding
Jun 2023
The Business Journals
The Funded: 12 Bay Area startups just raised a total of nearly $300M
Nov 2022
GlobeNewswire
Namecoach Lands $8 Million Series A to Advance DEI and End Name Butchering in the Workplace
Nov 2022
The Business Times
Koh Boon Hwee’s Altara Ventures leads US$5m fundraise for Thai proptech
Oct 2022
Newswire.com
Noteworthy AI Raises $3M to Increase Electric Grid Reliability, Resiliency and Safety via AI-Powered Asset Inspection
Jul 2022
Moneycontrol.com
8vdX raises $3 mn in seed round from Y Combinator, others
May 2022
VCCircle
Social commerce platform Gobillion raises funds led by YCombinator, JAM Fund, others
Dec 2021
YourStory.com
[Funding roundup] B2C social commerce startup Gobillion, fintech platform Minko raised early-stage investments
Dec 2021
Business Insider
Software Startup Stayflexi Used This Pitch Deck to Raise $1.6 Million
Jun 2021
Indian Transport & Logistics
Medical cargo drone startup Redwing Labs raises $1mn in seed round
Feb 2021
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Early-stage, first-money-in partner for technically ambitious founders transforming the physical world (energy, defense, infrastructure, space, advanced manufacturing), underwriting high technical and regulatory risk.
Early-stage investor in advanced tech and healthcare that funds companies with at least one female founder, focusing on STEM startups with female executives.
Research briefRead more
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