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.406 Ventures Fund

Boston, MA · Invests in US · Website

Thesis

Only invest where we have a true unfair advantage. Partner with founders in healthcare, data+AI, and cybersecurity to build category-defining powerhouses. We deliver value far beyond capital through deep domain expertise and extensive networks.

Likely not a fit for

No spray-and-pray investing. No generalist approach. No companies outside healthcare, data/AI, or cybersecurity without clear fit.

How they invest

Lead or follow
Usually leads
Typical decision
~2 weeks
Warm intro
Preferred
Involvement
Takes a board seat
Fund status
Actively deploying
Decision process
Partnership vote

Partners & team

7 contacts on file

GB

Graham Brooks

PartnerPartner · Primary contact

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g•••@40•••.com

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RR

Rebecca Redfield

PartnerPartner

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r•••@40•••.com

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LD

Liam Donohue

General PartnerCo-Founder and Managing Partner

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l•••@40•••.com

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PA

Payal Agrawal Divakaran

PartnerPartner

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p•••@40•••.com

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GD

Greg Dracon

PartnerPartner

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g•••@40•••.com

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KT

Kathryn Taylor Reddy

PrincipalPrincipal

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k•••@40•••.com

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MC

Maria Cirino

General PartnerFounding Managing Partner

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m•••@40•••.com

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Portfolio

Abacus InsightsHealthcare Digital

Abacus Insights manages healthcare data by breaking down data silos to make a real impact for our customers. Our platform standardizes data across the healthcare ecosystem by providing a highly secure unified data infrastructure that minimizes change management and maximizes analytics enablement to reduce costs and improve outcomes.

AristaMDHealthcare Digital

AristaMD is a technology-enabled clinical services provider that connects primary care physicians with specialists to improve access to specialty care and enhance patient outcomes while reducing costs.

AscellusHealthcare Digital

Ascellus provides work-focused cognitive behavioral therapy and behavioral health care services to support recovering workers in overcoming emotional distress and psychosocial factors that hinder recovery.

Better Life PartnersHealthcare Digital

Better Life Partners provides addiction treatment services, including medication-assisted treatment, group therapy, and mental health support, focusing on helping individuals overcome substance use disorders.

BobsledDeveloper Tools Infra

Bobsled is a modern data fulfillment platform that helps teams share, deliver, and customize datasets across clouds, regions, and tools—without the complexity of traditional pipelines.

Business Intelligence AdvisorsEnterprise Software

Business Intelligence Advisors (BIA) provides a range of services including professional development, expert analyst research, automated research, advisory services, due diligence, and special projects, focusing on markets such as public equity and private equity.

ChaosSearchEnterprise Software

ChaosSearch provides a platform for live analytics on streaming data at scale, enabling users to optimize their data stacks and replace traditional log analytics solutions.

ClosedLoopHealthcare Digital

ClosedLoop is an AI-powered analytics platform focused on improving health outcomes through predictive analytics tailored for various healthcare stakeholders including providers, payers, and life sciences.

Cortica CareHealthcare Digital

Cortica Care provides expert, all-in-one care for children with autism and developmental differences, including ABA therapy, medical services, and family support.

Diana HealthHealthcare Digital

Comprehensive Women’s Healthcare | In-Person & Virtual Care

EquipHealthcare Digital

Equip is transforming the landscape of eating disorder treatment with a 100% virtual, evidence-based treatment model designed to achieve full recovery for everyone affected by an eating disorder.

Genesis ComputingEnterprise Software

Genesis Computing delivers AI data agents with advanced built-in skills to automate critical data workflows, enhancing the data lifecycle and employee experiences in complex industries.

Recent activity

.406 Ventures Fund in the news

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Research briefRead more
.406 Ventures Fund Research Investment Thesis and Philosophy .406 Ventures models its investing philosophy after Ted Williams' legendary .406 batting average, believing that they should only swing at deals where they have a true unfair advantage rather than chasing every opportunity. The firm is selective and domain-focused, leveraging deep industry expertise and extensive networks to partner with

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