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Meridian Street Capital

New York, New York · Invests in US · Website

Check size

$100K-$5M

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Pre-SeedSeedSeries ASeries BB2B SaaSAI & Machine LearningDeveloper ToolsHealthcare & BiotechHealthcare & Digital HealthEnterprise SoftwareDeveloper Tools & Infrastructure

Thesis

We help turn the best ideas in healthcare into category-defining companies. The best healthcare companies emerge from disciplined partnerships with visionary founders combining technical expertise with healthcare domain knowledge.

Likely not a fit for

No pure consumer wellness, hardware-only solutions, or companies without meaningful clinical impact

How they invest

Lead or follow
Usually leads
Typical decision
~1 month
Warm intro
Preferred
Involvement
Takes a board seat
Fund status
Actively deploying
Decision process
Partnership vote

Partners & team

5 contacts on file

GR

George Ribaroff

Partner · Primary contact

JC

Jimmy Comfort

Venture Partner

SL

Scott Law

General Partner

BY

Brianna Yarnoff

Investor

RM

Robel Mulugeta

Investor

Portfolio

1upHealthHealthcare Digital

1upHealth makes it easy to acquire, manage, and use healthcare data through its modern data platform and APIs, ensuring secure and compliant exchange of timely data.

AnatomyFintech Payments

Anatomy is a financial technology company focused on automating financial operations for healthcare organizations, enabling them to streamline billing and revenue cycle management processes.

AndrosHealthcare Digital

Andros provides provider network management and medical credentialing services, focusing on lifecycle management solutions for healthcare networks.

BandEnterprise Software

Rebate and incentive management software to grow your business.

ClosedLoopHealthcare Digital

ClosedLoop is an AI-powered analytics platform focused on improving health outcomes through predictive analytics tailored for various healthcare stakeholders including providers, payers, and life sciences.

DecentFintech Payments

Decent provides a cross-chain infrastructure platform that enables seamless wallet onboarding, instant onramp and offramp for cryptocurrencies, and supports various use cases in the crypto ecosystem.

Dina CareHealthcare Digital

Dina Care is revolutionizing post-acute care by simplifying case management, reducing readmission rates, and improving the patient experience through a comprehensive platform that connects caregivers, technology, and data.

First DollarHealthcare Digital

First Dollar provides flexible infrastructure for health spending benefits, offering software and APIs for organizations to manage health spending programs effectively.

Hint HealthcareHealthcare Digital

Hint Health is a leading digital health company focused on Direct Primary Care, providing software and resources to support its growth. Hint powers over 2500 direct care organizations through its Core and Clinical solutions designed to accelerate the growth and adoption of Direct Care.

ImvariaHealthcare Digital

IMVARIA Inc. is a software-as-medical-device (SaMD) company pioneering AI-driven digital biomarker solutions that empower clinicians to make accurate diagnoses and prognoses at earlier stages of disease and reduce the need for invasive biopsy testing.

Included HealthHealthcare Digital

Included Health combines virtual and in-person care with expert navigation, comprehensive support, and AI-powered technology. The company aims to deliver world-class care that improves health outcomes and supports the mind, body, and wallet of every member they serve.

Isaac HealthHealthcare Digital

Isaac Health provides expert, personalized care for memory changes, Alzheimer’s, dementia, and other cognitive conditions, all from the comfort of home.

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Research briefRead more
Meridian Street Capital Research Investment Thesis Meridian Street Capital is dedicated to "engineering the future of healthcare alongside early stage trailblazers." The fund partners with exceptional founders at the intersection of healthcare and technology, with a focused investment philosophy that emphasizes deep specialization, early-stage entry, and concentrated portfolio support. The firm believes that the best healthcare companies emerge from disciplined partnerships with visionary founders who combine technical expertise with healthcare domain knowledge. Sector Focus Meridian Street Capital invests exclusively at the intersection of healthcare and technology, with a thematically coherent digital health portfolio. The firm focuses on: Digital Health Infrastructure : Platforms enabling better healthcare data exchange and interoperability (1upHealth) AI/ML Diagnostics : Companies leveraging machine learning for diagnostic improvement and clinical insights (Preemptive AI, Qualtech) Virtual Specialty Care : Telehealth and remote specialty care platforms (Included Health, Robin Healthcare) Women's Health : Reproductive and women's specific healthcare solutions Mental Health & Behavioral Health : Platforms addressing mental wellness and clinical behavioral health (Rula, Treat My OCD, Prava Therapy) Care Coordination : Patient engagement and care management tools (Ounce of Care, Band Health) Home-Based Care : Infusion therapy, homecare services (Local Infusion, Dina Care) Vertically-Integrated Healthcare : Specialized care delivery models The firm explicitly avoids pure consumer wellness, hardware-only solutions, and companies without meaningful clinical impact. Stage Focus Meridian Street Capital focuses on early-stage companies: Pre-Seed : $100K-$500K for founding teams and initial product development Seed : $500K-$2M for companies with initial customer traction and clinical validation Series A : $1M-$5M for companies achieving product-market fit with clear clinical outcomes The firm prioritizes being a founder's first institutional investor and leads or co-leads the majority of rounds. Check Size & Deployment Typical investment range: $100K - $5M Pre-seed: $100K-$500K Seed: $500K-$2M (most common) Series A: $1M-$5M (selective follow-ons) Fund status: Actively deploying . Recent investments include Quilt Health and Isaac Health (Series A, August 2025), indicating continued active deployment. Recent Activity & Portfolio Notable Recent Investments: Isaac Health (Series A, August 2025) Quilt Health (2025) Onboard AI (November 2025) - AI-powered enterprise healthcare systems Preemptive AI - Predictive health analytics Qualtech - Healthcare AI/quality measurement Readout - Health data analytics Portfolio Highlights (37+ companies): Exits & Acquisitions: Decent (acquired/partnership announced) First Dollar (acquisition) Hint (acquisition) Included Health (successful platform, acquired/grown) Tenure (acquisition) Valify (acquisition) Active Portfolio (Notable): 1upHealth - Healthcare data interoperability and API platform Anatomy - Visual healthcare technology Andros - Telehealth for men's health Band Health - Healthcare engagement platform Closed Loop - AI for healthcare operations Dina Care - Home care services Isaac Health - Healthcare navigation Jona Health - Primary care innovation Jukebox Health - Patient engagement through music therapy My Isaac Health - Healthcare management Ounce of Care - Preventive healthcare Prava Therapy - Mental health services Preemptive AI - Predictive health analytics Qualtech - Healthcare AI and measurement Quilt Health - Healthcare cost management Readout - Health data analytics Rula - Mental health services (therapist marketplace) Safe Ride Health - Non-emergency medical transportation Treat My OCD - Mental health/behavioral health On-Board AI - Enterprise healthcare AI Veracity Self Care - Digital therapeutics WURU - Healthcare technology Team Leadership: Scott Law (Partner, General Partner) - Senior investment leader at Meridian Street Capital George Ribaroff, MD (Partner) - Physician and healthcare venture investor with clinical background and deep industry expertise Investment Team: Brianna Yarnoff (Investor) - Healthcare investment professional Robel Mulugeta (Investor) - Healthcare investment professional Operations: Jimmy Comfort (Venture Partner) - Senior advisor to the firm The team uniquely blends venture capital expertise with deep clinical and healthcare domain knowledge. This healthcare-first orientation differentiates the firm. Geographic Focus Primary focus: United States , with headquarters in New York, New York . Decision Process & Founder Engagement Decision Structure : Partnership (Scott Law and George Ribaroff co-lead decisions) Decision Speed : Moderate (typical healthcare VC evaluation rigor for clinical validation) Warm Intros : Required (concentrated, relationship-driven fund) Involvement : Board seat or observer involvement typical Investment Philosophy & Differentiation Meridian Street Capital explicitly uses three key differentiators: Specialized - Deep focus exclusively on healthcare technology Early - Supporting founders often from day one Focused - Concentrated portfolio with steadfast partnership The firm prioritizes deep relationships and clinical impact over portfolio breadth. Founder Preferences The firm backs founders who: Have healthcare or clinical domain expertise Combine technical/business acumen with authentic healthcare problem identification Prioritize clinical outcomes and underserved patient populations Include diverse and underrepresented founders Fund Performance Portfolio Size : 37+ invested companies Exit Track Record : 6 known exits/acquisitions Active Deployment : Recent investments through November 2025 Founded : 2016 (approximately 9-10 years operating history)

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