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ZAKA VC

Prague, Czech Republic · Invests in US; UK; Europe · Website

Pre-SeedSeedB2B SaaSAI & Machine LearningDeveloper ToolsHealthcare & BiotechSpace & DefenseRoboticsBiotech & Life SciencesHealthcare & Digital HealthRobotics & AutomationEnterprise SoftwareDeveloper Tools & InfrastructureAerospace & Defense

Thesis

Founders backed by entrepreneurs. ZAKA bridges North American and CEE startup ecosystems, investing pre-seed to seed in Health & Biotech and Industrial Tech. The firm deploys institutional capital while leveraging operator networks to help European founders scale globally.

Likely not a fit for

No pure consumer social, late-stage growth equity, or non-scalable local services. Not a lead-only fund — comfortable co-investing.

How they invest

Lead or follow
Usually follows
Typical decision
~1 month
Warm intro
Not required
Involvement
Observer
Fund status
Actively deploying
Assets under mgmt
$18.7M
Decision process
Investment Committee

Partners & team

9 contacts on file

JB

Jan Buza

PartnerPartner · Primary contact

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j•••@za•••.vc

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SZ

Samo Zalesak

AssociateAssociate & Investment Committee Member

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s•••@za•••.vc

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JK

Jan Kasper

General PartnerCo-Founder & Managing Partner

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PZ

Peter Zalesak

General PartnerCo-Founder & Partner

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p•••@za•••.vc

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AP

Andrej Petrus

PartnerPartner & Head of Investment Committee

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a•••@za•••.vc

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NS

Natalia Sachova

Head of Portfolio and Communication

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n•••@za•••.vc

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RK

Richard Kopunik

Platform & OpsCOO

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r•••@za•••.vc

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FO

Filip Orth

InvestorHead of Investor Relations

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f•••@za•••.vc

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JM

Jozef Macak

AssociateAnalyst

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j•••@za•••.vc

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Portfolio

CellType
SygaldryEnterprise Software

Sygaldry is building quantum-accelerated AI servers to exponentially speed up training and inference, integrating quantum capabilities into AI models and workflows for the development of secure superintelligence.

HexemBioBiotech Life Sciences

HexemBio is focused on reversing aging through advanced stem cell therapy, specifically targeting the rejuvenation of hematopoietic stem cells to improve blood cell production and overall health.

MewsEnterprise Software

Mews is a cloud-native property management system (PMS) designed for the hospitality industry, enabling hotels and other accommodation providers to automate operations, enhance guest experiences, and increase revenue through a single intuitive platform.

Zephyr FusionClimate Clean Energy

Zephyr Fusion is focused on developing compact megawatt class fusion reactors to power the space economy, including applications in microgravity manufacturing, data centers, defense, transport propulsion, and human habitation.

Kano TherapeuticsBiotech Life Sciences

Kano Therapeutics specializes in circular single-stranded DNA (cssDNA) for genetic medicine, providing innovative solutions for gene therapy and editing through scalable manufacturing processes.

LunabillHealthcare Digital

LunaBill automates medical billing calls using AI voice agents to handle tedious insurance calls, including claim status inquiries, A/R recovery, and appeal follow-ups. The platform integrates seamlessly with existing EHR or PM systems and requires no workflow changes.

Verne RoboticsRobotics Automation

Verne Robotics builds intelligent machines, specifically mobile, dual-arm robots designed for automating warehouse operations such as bin picking, packing, and sorting. Their robots are reconfigurable on-site and aim to enhance efficiency in fulfillment and logistics.

Avelis HealthHealthcare Digital

Avelis Health provides AI-powered auditing of medical claims to enhance payment integrity for third-party administrators (TPAs) and health plans. Their services include identifying billing errors, recovering overpayments, and utilizing voice AI agents for dispute resolution.

B12Enterprise Software

B12 is an AI-powered website builder that allows users to create and customize their online presence easily, without the need for coding or design skills. It offers a range of templates and tools to help businesses launch their websites quickly and efficiently.

NephrogenBiotech Life Sciences

Nephrogen is a Stanford/Harvard biotech spinout commercializing an AI screening platform to solve gene delivery for serious diseases, specifically targeting kidney and pancreatic diseases.

Bullseye Biosciences

Recent activity

ZAKA VC in the news

Research briefRead more
ZAKA VC Research Investment Thesis ZAKA VC is a Prague and Silicon Valley-based seed and pre-seed fund founded in 2020 by serial entrepreneur Jan Kasper and Peter Zalešák as a family office. The fund formally transitioned to an institutional venture capital vehicle with the announcement of Fund I (€15M target, €10.5M first close) in July 2024. ZAKA's core thesis centers on bridging the North Ameri

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