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Two Sigma Ventures

New York, NY · Invests in US; UK; Asia; LATAM; Europe · Website

SeedSeries ASeries BB2B SaaSAI & Machine LearningDeveloper ToolsData & AnalyticsCybersecurityFintechBiotech & Life SciencesEnterprise SoftwareFintech & PaymentsDeveloper Tools & InfrastructureSecurity & CybersecurityHealthcare & Digital HealthReal Estate & PropTechRobotics & Automation

Thesis

As the world becomes more information-rich, most transformative new companies will leverage data science, machine learning, and advanced computing power. We back founders building breakthrough solutions at this intersection.

Likely not a fit for

Pure consumer apps without data angles, services-based businesses, non-technical founding teams, hardware without significant software components

How they invest

Lead or follow
Usually leads
Typical decision
~1 month
Warm intro
Preferred
Involvement
Takes a board seat
Fund status
Actively deploying
Assets under mgmt
$60B
Decision process
Partnership vote

Partners & team

9 contacts on file

SN

Sachin Nagpal

PartnerPartner · Primary contact

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n•••@tw•••.com

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ES

Eric Stricko

PartnerPartner

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e•••@tw•••.com

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CB

Colin Beirne

PartnerPartner

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X profile

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DP

Dusan Perovic

PartnerPartner

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DA

Dan Abelon

PartnerPartner

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SC

Sidney Costabile

PartnerPartner

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FS

Frances Schwiep

PartnerPartner

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JB

Joe Botsch

PrincipalPrincipal

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VI

Villi Iltchev

PartnerPartner

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Portfolio

Recursion PharmaceuticalsBiotech Life Sciences

Recursion Pharmaceuticals uses AI to discover new drugs, aiming to reduce the high failure rate of traditional drug discovery. They partner with industry leaders and leverage advanced data and machine learning models.

WHOOPHealthcare Digital

WHOOP provides professional-grade fitness insights and advanced health, fitness, and longevity insights through a membership model, focusing on unlocking human performance and healthspan.

InsitroBiotech Life Sciences

Insitro is a drug discovery company that leverages machine learning and large-scale data to develop new medicines more efficiently. They focus on understanding complex biological systems to create transformative therapies in areas such as metabolism, oncology, and neuroscience.

EnigmaEnterprise Software

Enigma provides comprehensive intelligence about the identity and financial health of small and medium businesses across the United States. By engineering better data from hundreds of public and third-party sources, Enigma tells the complete story of every business, so that companies of every size can access the financial services they need to grow and thrive.

GitLabEnterprise Software

GitLab is the most comprehensive AI-powered DevSecOps platform used by more than 100,000 organizations to deliver software faster, more efficiently, while strengthening security and compliance.

RemoteHr Tech Work

Remote& provides a comprehensive platform, PeopleOS, for GCC companies managing borderless workforces. It facilitates hiring, payroll, compliance, and support through an AI-native system designed to handle global teams efficiently.

Prairie HealthHealthcare Digital

Carbon Health offers modern primary and urgent care services, accepting all major insurance providers. They provide same-day appointments and utilize technology to improve healthcare.

CoverWalletFintech Payments

CoverWallet is a digital insurance platform that allows businesses to manage their insurance policies online, including making payments, obtaining certificates of insurance, and accessing policy documents.

KasistoFintech Payments

Kasisto is a leader in AI-powered experiences for financial institutions, providing solutions that enhance customer engagement and operational efficiency through predictive and generative AI.

Pro.comEnterprise Software

Pro.com is an innovative general contractor that helps you realize your construction goals ranging from small home renovations to new home builds.

PlacedMarketing Adtech

Placed provides location intelligence solutions that help marketers measure the effectiveness of their advertising campaigns by connecting campaign exposure to real-world conversions.

Amper MusicEnterprise Software

Amper Music is a company that offers AI-driven tools for generating images from text.

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Research briefRead more
Two Sigma Ventures Research Investment Thesis Two Sigma Ventures is the venture capital arm of Two Sigma Investments, LP, a $••+ quantitative hedge fund and financial sciences company. Founded in 2011, the firm invests with the conviction that as the world becomes increasingly information-rich, transformative new companies will leverage data science, machine learning, and advanced computing power

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