SOSV

unspun is a fashion and technology company focused on revolutionizing the apparel manufacturing process through 3D weaving technology, aiming to reduce waste and carbon emissions in the fashion industry.

Upside Foods is a pioneer in cultivated meat, offering delicious chicken products grown directly from animal cells, aiming to provide a more humane and sustainable alternative to traditional meat production.

Prolific Machines is a biotechnology company that specializes in advanced biomanufacturing solutions using its Photomolecular™ platform, which integrates optogenetic technology and AI-driven bioprocess optimization to enhance the production of biotherapeutics.

Proton Intelligence is building the first real-time, on-demand potassium monitoring wearable, allowing clinicians to treat and manage kidney disease patients more safely and precisely.

Hoofprint Biome is developing probiotics and natural enzymes that improve cattle health and yield while eliminating methane emissions, promoting sustainable agriculture through symbiotic livestock production.

FluoSphera is revolutionizing in vitro drug discovery with its proprietary chip-free technology, offering high-throughput solutions that accurately mimic human physiology. By utilizing advanced 3D tissue multiplexing, FluoSphera enables researchers to study human responses to systemic drug delivery, enhancing the speed and effectiveness of pre-clinical evaluations.

Co-founder-focused fund for lab-based teams at the health–climate intersection (gene therapy, synthetic biology, batteries), offering deep access to UC Berkeley, UCSF, MIT and Stanford research and scientist-founders. Blue Bear Ventures spun out of UC Berkeley's CITRIS Foundry deep tech accelerator and maintains unique relationships with top research labs at UC Berkeley, UCSF, MIT, and Stanford, giving them unusually deep access to scientist-founders and university research. The fund focuses specifically on co-founding teams from labs working at the intersection of health and climate—such as gene therapy, synthetic biology, and next-generation batteries—rather than investing in lone founders or abstract ideas.

Invests in disruptive, technology-focused startups; established in 1999.

Early institutional backer that sources tech from academia and government labs, partnering with scientist- and engineer-led teams to deeply interrogate science, dual-use/defense opportunities, and amplify through an in-house media platform. Explicitly aims to "turn science fiction into science fact" by backing companies at the intersection of the new and the not-yet-imagined, built around scientists, engineers, and polymaths rather than traditional finance backgrounds who can deeply interrogate emerging science and complex tech. The firm systematically mines academia and government labs for "technological gems" and has become one of the earliest institutional backers of dual-use and defense technology.

Targets companies addressing labor shortages in manufacturing, construction, logistics, and food production; cutting healthcare costs from aging and chronic disease; and enabling sustainable food production for growing populations.

Pre-seed lead investor for deeply technical AI, biotech, climatetech and infrastructure startups, offering female operator-led go-to-market expertise and structured fellowships to source technical-founder deal flow. Divergent Capital is run by two female operator-investors who combine deep-tech investing experience with hands-on go-to-market expertise, and they cultivate deal flow through structured fellowships targeting students and emerging investors in their technical-founder network.