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Health Technology Holding (HTH)

Milan, Italy · Invests in Europe; North America; MENA; US

Thesis

Science-driven venture capital focused on breakthrough healthcare innovations. Deep scientific rigor in diligence with mechanism-of-action understanding, proof-of-concept validation, and extensive KOL/clinician engagement. Backed by Zambon Group pharmaceutical expertise.

Likely not a fit for

Not a lead investor for large rounds. Does not compromise on scientific merit for market size. Requires warm introductions and patient capital deployment model.

How they invest

Lead or follow
Usually follows
Typical decision
~2 months
Warm intro
Preferred
Involvement
Takes a board seat
Fund status
Actively deploying
Decision process
Partnership vote

Partners & team

1 contact on file

MG

Michele Gaiotto

CEO · Primary contact

+ Pitch

Portfolio

SOM BiotechBiotech Life Sciences

SOM Biotech is a late clinical-stage biopharmaceutical company focused on discovering and developing new impactful treatments for rare diseases of the CNS using an AI-driven platform for drug discovery.

NeurofenixHealthcare Digital

Neurofenix is a tech-enabled virtual care provider that helps neurological patients achieve their rehabilitation goals at home through personalized, engaging, and evidence-based therapy programs.

SeaBeLifeBiotech Life Sciences

SeaBeLife is a biotechnology company developing innovative small molecules that simultaneously target two major regulated cell death pathways - necroptosis and ferroptosis - designed to address major unmet medical needs in acute, rare and chronic indications.

Hyivy HealthHealthcare Digital

Hyivy Health is a woman-owned company focused on pelvic health rehabilitation, providing innovative solutions for patients and clinicians. Their mission is to improve the standard of care for pelvic health issues through holistic, patient-centered approaches and advanced technology.

EndostartBiotech Life Sciences

Endostart is a startup focused on the development and manufacturing of a new generation of medical devices for gastrointestinal endoscopy, utilizing innovative Magnetic Balloon Technology.

EpilepsyGTXBiotech Life Sciences

EpilepsyGTx is a late preclinical-stage biotech developing cutting-edge gene therapies that will transform the management of focal refractory epilepsy (FRE).

LeukoHealthcare Digital

Leuko is developing PointCheck™, the first device for non-invasive white blood cell monitoring. This portable device allows for fast and simple assessment of white blood cell levels without the need for blood draws, aiming to improve the quality of life for immunosuppressed patients.

Lys TherapeuticsBiotech Life Sciences

Lys Therapeutics is a biotechnology company developing first-in-class monoclonal antibodies to treat patients suffering from neurodegenerative and neurovascular diseases with high unmet medical needs.

Recent activity

Health Technology Holding (HTH) in the news

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Research briefRead more
Health Technology Holding (HTH) Research Investment Thesis Health Technology Holding (HTH) is a specialized life sciences venture capital firm dedicated to identifying and supporting breakthrough innovations in healthcare. Founded in 2020 as part of ZCube-Zambon Research Venture, HTH is backed by the Zambon Group, a global pharmaceutical company with deep expertise in pharmaceutical development an

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