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Friale

San Francisco, CA · Invests in US; North America; Europe; Africa; Asia; MENA · Website

Pre-SeedSeedSeries AB2B SaaSAI & Machine LearningDeveloper ToolsFintechHealthcare & BiotechClimate & EnergyEnterprise SoftwareHealthcare & Digital HealthDeveloper Tools & InfrastructureFintech & PaymentsClimate & Clean Energy

Thesis

Much of the world's software will be reimagined in the age of AI's compounding innovation cycle. We partner with the best founders across all verticals who are seizing this opportunity, with particular emphasis on healthcare transformation and AI applications.

Likely not a fit for

Heavily capital-intensive hardware without software differentiation; teams without clear go-to-market understanding; founders not aligned on vision

How they invest

Lead or follow
Usually leads
Typical decision
~2 weeks
Warm intro
Not required
Involvement
Takes a board seat
Fund status
Actively deploying
Decision process
Partnership vote

Partners & team

2 contacts on file

NA

Nick Alexander

InvestorEarly-Stage Investor · Primary contact

+ Pitch

n•••@fr•••.com

LinkedIn profile

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BF

Bryan Frist

General PartnerFounder & Managing Partner

+ Pitch

b•••@fr•••.com

LinkedIn profile

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Portfolio

GrowwFintech Payments

Groww is an online platform for Demat, trading, and direct mutual fund investment in India, offering services like stock trading, mutual funds, and futures & options.

BillionToOneHealthcare Digital

BillionToOne is a molecular diagnostics company focused on creating accessible prenatal screening and liquid biopsy tests.

Ambience HealthcareHealthcare Digital

Ambience Healthcare provides an AI platform designed to streamline documentation and coding processes for healthcare providers, reducing clinician burnout and improving patient care across various specialties.

Fly.ioDeveloper Tools Infra

Fly.io is a global platform for running web, AI, and app servers close to users. It offers an Application Delivery Network and is used by developers to deploy Docker images.

SolugenManufacturing Industrial

Solugen is redefining chemical manufacturing by harnessing the power of biology and chemistry to create sustainable chemical solutions for various industries, including oil and gas, renewable fuels, and agriculture.

LivelyFintech Payments

Lively offers flexible employee benefits and Health Savings Accounts (HSAs) for brokers and businesses, focusing on long-term health savings and pre-tax health reimbursements.

YoshiEnterprise Software

Yoshi Mobility provides certified digital vehicle inspections, performed virtually, to keep vehicles on the road. Their services include rideshare inspections, DOT inspections, and EV fast-charging solutions.

AI Healthcare Platform Co.
Diagnostic AI Solutions
Healthcare Cloud Infrastructure
Clinical Operations AI
Medical Device SoftwareHealthcare Digital

MedDev Soft helps medical and digital health companies bring their products to market, specializing in software development, regulatory processes, quality assurance, verification & validation, cybersecurity, and risk management for medical devices.

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Research briefRead more
Friale Research Investment Thesis Friale is an early-stage generalist fund with a distinctive bend towards AI and healthcare. The fund believes that much of the world's software will be reimagined in the age of AI's compounding innovation cycle. The team actively seeks to partner with the best founders across all verticals who are seizing this opportunity, with particular emphasis on AI applicatio

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