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Flagship Pioneering

Cambridge, Massachusetts · Invests in US; Europe; Global · Website

Thesis

Create first-in-category bioplatform companies through scientific innovation and systematic entrepreneurship. Combine institutional scale with pioneer creativity to build breakthrough life sciences companies.

Likely not a fit for

No late-stage companies competing in mature markets. No pure software or digital-only businesses. Emphasis on biological and scientific innovation, not technology for technology's sake.

How they invest

Lead or follow
Usually leads
Typical decision
~1 month
Warm intro
Preferred
Involvement
Takes a board seat
Fund status
Actively deploying
Assets under mgmt
$14B
Decision process
Investment Committee

Partners & team

3 contacts on file

NA

Noubar Afeyan

General PartnerFounder & CEO · Primary contact

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LinkedIn profile

X profile

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MG

Molly Gibson

PartnerOrigination Partner

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AR

Adrian Rawcliffe

PartnerCEO-Partner and CEO of Etiome

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Portfolio

ModernaEcommerce Marketplaces

Refaccionaria Moderna is a leading automotive parts supplier in northern Mexico, with over 70 years in the market and multiple branches strategically located in metropolitan Monterrey and other states.

Tessera TherapeuticsBiotech Life Sciences

Tessera Therapeutics is pioneering Gene Writing™, a new genome engineering technology that writes therapeutic messages into the genome to treat diseases at their source.

Generate BiomedicinesBiotech Life Sciences

Generate Biomedicines is focused on leveraging advanced computational techniques to design and develop new therapeutic proteins, particularly in the field of biomedicine.

Inari Agriculture
Quotient TherapeuticsBiotech Life Sciences

Quotient Therapeutics is pioneering somatic genomics to transform genetically-validated targets into breakthrough medicines, unlocking new therapeutic strategies for various diseases.

Lila SciencesBiotech Life Sciences

Lila Sciences is the world’s first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are building the foundation to apply AI to every aspect of the scientific method, enabling scientists to bring forth solutions in human health and sustainability at a pace and scale never experienced before.

Valo HealthBiotech Life Sciences

Valo Health is redefining drug discovery by combining real-world data, AI, advanced causal inference techniques, and predictive chemistry to create a powerful drug discovery and development engine.

Vesalius Therapeutics
Profound TherapeuticsBiotech Life Sciences

Profound Therapeutics focuses on novel proteins from the human genome. They aim to elucidate their functions.

Sana BiotechnologyBiotech Life Sciences

Sana Biotechnology is focused on engineered cells as medicines, aiming to repair and control genes or replace missing or damaged cells to address the underlying causes of diseases.

KSQ Therapeutics
Seres TherapeuticsBiotech Life Sciences

Seres Therapeutics is a clinical stage biotechnology company developing new therapies comprised of rationally selected live bacteria consortia to modulate the human microbiome and revolutionize treatment for serious diseases.

Recent activity

Flagship Pioneering in the news

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Research briefRead more
Flagship Pioneering Research Overview Flagship Pioneering is a preeminent venture capital and innovation firm that operates on an unprecedented model of institutional innovation. Founded in 2000 by Noubar Afeyan, Flagship has redefined venture capital by positioning itself not as a traditional investor but as a principal founder, funder, and operator of breakthrough companies. Operating with $••

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