First Star Ventures
Boston, Massachusetts · Invests in US · Website
Check size
🔒 $•• – $••Thesis
Invest with conviction in visionary, technical founders inventing the future with frontier computing technology. Focus on computing×real-world startups (techbio, climate, robotics, industrial infrastructure). Enforce strict rebuildability bar—won't invest if 3-5 Google engineers could recreate product in 3-12 months. Position against SaaS/consumer playbook; future venture outliers will be very different.
Likely not a fit for
No non-technical founders, no commoditized SaaS, no consumer-only apps, no investments that fail rebuildability bar
How they invest
- Lead or follow
- Usually follows
- Typical decision
- ~2 weeks
- Warm intro
- Preferred
- Involvement
- Advisor
- Fund status
- Actively deploying
- Decision process
- Partnership vote
Partners & team
3 contacts on file
Portfolio
Software Engineering Intelligence Platform that helps organizations effectively manage engineering teams, improve operational efficiency, and align engineering work with business outcomes.
Zanskar is an AI-native geothermal energy company focused on unlocking geothermal resources using data and advanced technologies to deliver affordable, carbon-free energy.
Enzymit is pioneering a new era of biomanufacturing through the creation of novel enzymes that address unmet market needs, focusing on cell-free production methods that are faster, simpler, cost-effective, and sustainable.
Nomic.bio offers affordable and flexible proteomics solutions, including the Omni 1000 platform that quantifies 1000 informative proteins with high fidelity. Their nELISA technology revolutionizes multiplexed immunoassays, enabling high-throughput protein profiling.
Salient Predictions provides AI-powered weather forecasts and analytics, leveraging machine learning and deep neural networks to deliver accurate predictions from daily to yearly timeframes, with applications in various industries including agriculture, energy, and finance.
Scoot Science provides the SeaState platform, which transforms environmental, fish inventory, and operations data into site-specific ocean forecasts and fish health insights for fish farms.
EnPowered helps you transform your electricity use into new revenue and bottom-line savings. Our expert guidance and AI-assisted technology make participation in energy market programs easy without disrupting your core revenue-generating operations.
Gradient Technologies offers a passwordless multi-factor authentication (MFA) solution that eliminates traditional authentication methods, providing a frictionless user experience while enhancing security against credential-based cyberattacks.
Turso is the lightweight database that scales to millions of instances, designed for the agentic future. It serves as a complete SQLite drop-in replacement, built to support AI agents and intelligent applications by deploying databases everywhere, including servers, browsers, and devices.
VistaPath is modernizing pathology labs using computer vision and artificial intelligence. They provide clients with significant quality, workflow, and strategic benefits with the overall goal of delivering improved results for pathologists, clinicians, and patients. The Sentinel is the company’s first product.
Native Voice Studios develops AI companions based on fully licensed characters, distributing them on various devices to foster engagement and entertainment. They focus on creating compliant, high-quality AI interactions.
Kanary is a web app designed for personal data removal, offering self-guided and fully-managed services to help users remove their personal information from data brokers and the internet.
Recent activity
- Nov 2025
Extellis
Pre-Seed · Lead
- Oct 2025
iOrganBio
Seed · Lead
- Jan 2025
Bedrock Energy
Seed · Participated
First Star Ventures in the news
dallasinnovates.com
Houston's Bot Auto Partners With Ryan on 'Humanless' Freight Runs Between Dallas and Houston
6 months ago
Global Venturing
Saudi Arabia’s KAUST university seeks global VC money after spinouts raise $1bn
7 months ago
Failory
Top 21 Venture Capital Firms in Cambridge (2026)
8 months ago
Hypepotamus
After the Funding Round: Durham-based Extellis Sets Its Sights On Orbit After $6.8 Million Seed Round
9 months ago
Startups Magazine
KAUST startups surpass $1 billion in global investments
9 months ago
InnovationMap
Houston autonomous trucking co. completes first test run without human intervention
11 months ago
MassLive
Six things to know about the Circle crypto IPO, happening this week
Jun 2025
InnovationMap
14 Houston startups start 2025 with fresh funding
Jan 2025
mbo.atn.mybluehost.me
Canadian startup Phaseshift raises $3 million in investment led by Innospark Ventures and others
Oct 2024
BetaKit
Phaseshift Technologies raises $4.1 million CAD to fuse material discovery with AI
Oct 2024
InnovationMap
Houston-based Bot Auto raises $20M
Oct 2024
calcalistech.com
Enzymit raises $10 million Series A for cell-free bio-production technology
Sep 2024
The Business Journals
Funding wrap: Saronic Technologies lands $55M funding; Multimillion-dollar raise fuels geothermal energy startup
Oct 2023
Business Insider
The 52 most important VCs in Boston, according to other VCs
Oct 2023
Inside Precision Medicine
Biology Modeling Company Genialis Raises $13M in Series A Financing
Mar 2023
Business Insider
The 41 most important VCs in Boston, according to other VCs
Sep 2022
AgFunderNews
The Week in Agrifoodtech: Fazenda Futuro nets $58m; Growers Edge buys FarmlandFinder assets
Nov 2021
AgFunderNews
EXCLUSIVE: Biopesticide startup Robigo raises pre-seed funding to make 'molecular vigilantes'
Nov 2021
The Business Journals
Venture capitalists split on whether change to the Volcker Rule will benefit new funds
Sep 2020
Crypto Briefing
Sia’s Parent Company Raises $3 Million and Launches Rebrand
Sep 2020
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