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F-Prime Capital

Cambridge, Massachusetts · Invests in US; Europe; Asia · Website

Pre-SeedSeedSeries ASeries BB2B SaaSAI & Machine LearningDeveloper ToolsFintechHealthcare & BiotechEducationBiotech & Life SciencesHealthcare & Digital HealthFintech & PaymentsEnterprise SoftwareDeveloper Tools & InfrastructureClimate & Clean Energy

Thesis

Partner with visionary founders to turn bold ambitions into world-changing breakthroughs in life sciences, technology, healthtech, and crypto. Distinctive 'technical-risk-yes, regulatory-risk-no' filter ensures clear pathways to success.

Likely not a fit for

Avoid founders without deep domain expertise. Avoid regulatory-heavy categories without clear FDA pathways.

How they invest

Lead or follow
Usually leads
Typical decision
~1 week
Warm intro
Not required
Involvement
Takes a board seat
Fund status
Actively deploying
Assets under mgmt
$5.3B
Decision process
Partnership vote

Partners & team

9 contacts on file

NS

Nihal Sinha

PartnerPartner · Primary contact

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n•••@fp•••.com

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DN

David Needell

PartnerPartner

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d•••@fp•••.com

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SK

Stephen Knight

General PartnerPresident & Senior Managing Partner

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DJ

David Jegen

General PartnerManaging Partner, Tech Fund

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d•••@fp•••.com

LinkedIn profile

X profile

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SA

Sanjay Aggarwal

Venture PartnerVenture Partner

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HK

Harlan Krumholz

Venture PartnerVenture Partner

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CB

Carl Byers

Partner

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JL

Jon Lim

PartnerPartner

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j•••@fp•••.com

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KC

Kevin Chu

PrincipalPrincipal

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k•••@fp•••.com

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Portfolio

Beam TherapeuticsBiotech Life Sciences

Beam Therapeutics is a biotechnology company focused on developing precision genetic medicines using base editing technology to treat serious diseases.

Denali TherapeuticsBiotech Life Sciences

Denali Therapeutics is focused on developing therapies for neurodegenerative diseases using their proprietary TransportVehicle™ platform.

Ultragenyx PharmaceuticalsBiotech Life Sciences

Ultragenyx Pharmaceutical Inc. is a biopharmaceutical company focused on the development of innovative products for the treatment of rare and ultra-rare diseases.

ToastEnterprise Software

Toast is a powerful POS system designed specifically for the restaurant industry, enhancing the guest experience through modern technology.

FlywireFintech Payments

Flywire is a global payments company that specializes in providing payment solutions tailored for various industries, including education, travel, healthcare, and B2B.

Ironwood PharmaceuticalsBiotech Life Sciences

Ironwood Pharmaceuticals is focused on developing innovative treatments for gastrointestinal (GI) health, with a strong emphasis on improving patient outcomes through advanced therapeutic solutions.

InsmedBiotech Life Sciences

Insmed is a global biopharmaceutical company focused on the development and commercialization of innovative therapies for patients with serious diseases. The company emphasizes a patient-first approach and is committed to advancing science sustainably and ethically.

SeyondRobotics Automation

Seyond is a global provider of high-performance LiDAR systems, specializing in applications for autonomous driving, intelligent transportation systems, robotics, and industrial automation.

Iora HealthHealthcare Digital

Iora Health is a primary care practice focused on providing affordable, accessible, and enjoyable healthcare through a blend of human-centered design and technology. It serves Medicare patients with a value-based care model.

Blueprint MedicinesBiotech Life Sciences

Blueprint Medicines is focused on developing innovative therapies for patients with mast cell disorders and solid tumors, utilizing a proven drug discovery platform and robust clinical development infrastructure.

Prime MedicineBiotech Life Sciences

Prime Medicine is focused on transforming the lives of patients with debilitating diseases through its Prime Editing technology, a next-generation gene editing approach that aims to correct genetic mutations at their precise locations in the genome.

Sana BiotechnologyBiotech Life Sciences

Sana Biotechnology is focused on engineered cells as medicines, aiming to repair and control genes or replace missing or damaged cells to address the underlying causes of diseases.

Recent activity

F-Prime Capital in the news

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Research briefRead more
F-Prime Capital Research Investment Thesis F-Prime Capital is a global venture capital firm with a distinctive heritage spanning over 50 years, emerging from Fidelity Investments' venture capital division (founded in 1969 as Fidelity Ventures). The firm operates as an independent subsidiary of Fidelity with no outside investors, managing $5.3 billion in assets under management. F-Prime's core thes

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