Cortical Ventures

Alpha-Z provides a reasoning layer that helps robots operate reliably in complex, dynamic environments, enabling them to think, adapt, and act autonomously across various sectors such as security, construction, and industrial operations.

E2B is an open-source runtime for executing AI-generated code in secure cloud sandboxes, designed for agentic and AI use cases.

Fal is a generative AI platform that provides APIs for developers to run image, video, and audio models quickly and efficiently. It offers a library of over 600 production-ready models and serverless GPU options for scalable AI applications.

Integration.app provides an AI-powered platform called Membrane that enables users to build, test, and maintain product integrations quickly and efficiently. It automates the integration process, allowing software products to connect seamlessly without extensive manual coding.

Kyber Labs is building a robotic manipulation platform designed for AI-based controls, featuring low-cost hardware that mimics human-like dexterity for delicate manipulation tasks at scale.

Neo Cybernetica is developing novel cybernetics technology by leveraging breakthroughs in neuroscience, cognitive sciences, artificial intelligence, simulation, and robotics.

Predator AI is building foundational geospatial models for the real world, solving GPS-denied navigation for robotic systems in contested environments.

AngelQ is a kid-first super browser that uses AI to create a safer, smarter internet for families, prioritizing the needs and experiences of children.

hOS is a technology startup focused on developing AI-driven technologies aimed at maximizing prosperity and minimizing suffering.

DataroomHQ provides a secure platform for creating investor-ready datarooms, allowing users to upload documents and automatically generate key financial assets like data decks and investor memos. The platform offers granular permissions and tracks investor engagement.

Claryo is a leading provider of Spatial Generative AI, offering a turnkey solution to upgrade warehouse ecosystems through AI-powered virtual facilities.

OpenAI Startup Fund is the venture arm of OpenAI, investing in exceptional engineers, designers, researchers, and product builders using AI to reimagine products and industries. The fund runs Converge, a highly selective five-week program for founders building with AI.

Basis Set Ventures is a $140M+ seed fund that uses psychometrics and structured data to categorize founders into specific archetypes (like "humble operator" or "agile visionary"), then statistically models which personality patterns correlate with outlier outcomes—turning typical "gut feel" investing into a repeatable, data-informed process. The women-led firm runs a quantitative sourcing engine that tracks obscure signals like GitHub activity spikes and engineer departures from big tech to find "future of work" AI companies outside the usual Sand Hill Road network, positioning itself as the place where introverted, pragmatic operators can practice their pitch and get hands-on help with everything from go-to-market strategy to model-building.

Active AI builders operating Imbue and training 100B+ models give founders direct partner access, investing early with small non-lead checks that slot alongside top-tier leads and maximize helpfulness per dollar.